- 029-86354885
- 18392009562
抗體藥物偶聯物 (ADC) 是一種蛋白質—通常為單克隆抗體 (mAb)——通過ADC交聯劑共價結合(偶聯)到小分子藥物。 mAb的定位能力與強效抗癌藥物相結合,可敏感地辨析健康細胞和患病細胞。 鑒于偶聯藥物的效力,開發這些生物治療藥物比單獨開發mAb更加困難,包括設計用于詳細表征ADC的 UHPLC系統、質譜系統和LC色譜柱,能讓您更方便地分離和表征這些新型分子。
ADC藥物的藥效和清除率都與藥物抗體偶聯比(DAR)值有關,因此在藥物開發過程中必須對其精確分析。尺寸排阻色譜法和疏水色譜法是在天然生理條件下檢測DAR的兩種最常用的方法。
相關資料:
Mouse Anti-vc-PAB-MMAE mAb (B11F11)
Rabbit Anti-MMAF pAb
Mouse Anti-MMAF mAb (F3B11)
Mouse Anti-MMAE / F mAb (B12A2)
Mouse Anti-MMAE /F mAb (C12A1)
Rabbit Anti-DM1/4 pAb
Mouse Anti-DM1/4 mAb (F1D5)
Mouse Anti-DM1/4 mAb (G2F3)
Rabbit Anti-Calicheamicin pAb
Mouse Anti-Calicheamicin mAb (B1G9)
Mouse Anti-Calicheamicin mAb (C1F12)
Rabbit Anti-Duocarmycin pAb
Mouse Anti-Duocarmycin mAb (E11A1)
Mouse Anti-Duocarmycin mAb (H7A9)
Mouse Anti-Duocarmycin mAb (E6B3)
Rabbit Anti-PNU-159682 pAb
Mouse Anti-PNU-159682 mAb (F7F2)
Mouse Anti-PNU-159682 mAb (C1E3)
Mouse Anti-PNU-159682 mAb (D12H11)
Rabbit Anti-Amanitin pAb
Mouse Anti-Amanitin mAb (H3E1)
Mouse Anti-Amanitin mAb (H12D6)
Mouse Anti-Amanitin mAb (C2C4)
Rabbit Anti-SN38 pAb
Mouse Anti-SN38 mAb (10F11A9D6)
Mouse Anti-SN38 mAb (8E10F12F3)
Mouse Anti-SN38 mAb (8E10A4A1)
Rabbit Anti-PBD SG3199 pAb
Mouse Anti-PBD SG3199 (7H6H9A6) mAb
Mouse Anti-PBD SG3199 (8G2H12A9) mAb
Mouse Anti-PBD SG3199 (8B3D12G1) mAb
Dolastatin 10 Cas號:110417-88-4 微管蛋白聚合抑制劑
Monomethyl Dolastatin 10 Cas號:203849-91-6單甲基澳瑞他汀
Auristatin E Cas號:160800-57-7 澳瑞他汀
Monomethyl Auristatin E 474645-27-7微管相關抑制劑
Auristatin F Cas號:163768-50-1 澳瑞他汀
Monomethyl Auristatin F Cas號:745017-94-1
HTI-286 228266-40-8
Tubulysin M 205304-86-5
Maytansinoid AP-3 66547-09-9
Maytansinol 57103-68-1
DM1 139504-50-0
DM4 799840-96-3
Boc-Val-Dil-Dap-OH
Boc-Val-Dil-Dap-Phe-OMe
Boc-Val-Dil-Dap-Doe
Boc-Val-Dil-Dap-Nrp
Boc-N-Me-Val-Val-Dil-Dap-OH
Tubulysin IM-1
Tubulysin IM-2
Tubulysin IM-3
Duocarmycin SA 152785-82-5
Duocarmycin TM
Duocarmycin MA
Duocarmycin DM
Nemorubicin 108852-90-0
PNU-159682 202350-68-3
Calicheamicin g1 108212-75-5
Acetyl-Calicheamicin g1 108212-76-6
a-Amanitin 23109-05-9
PBD-dimer 1222490-34-7
序號 | 新聞標題 | 瀏覽次數 | 作者 | 發布時間 |
---|---|---|---|---|
1 | 抗氧化小分子70831-56-0,菊苣酸Cichoric Acid,6537-80-0的制備過程 | 741 | 瑞禧生物 | 2023-03-30 |
2 | 活性氧ROS小分子Dapsone,cas:80-08-0,氨苯砜的制備過程-瑞禧科研 | 659 | 瑞禧生物 | 2023-03-30 |
3 | HBPS-N3,Azide-PEG-HBPS,疊氮化超支化聚苯乙烯高分子聚合物的制備過程 | 769 | 瑞禧生物 | 2023-03-17 |
4 | l-PS-PhN3,Azide疊氮Azido偶聯線性聚苯乙烯雙鏈的制備過程 | 716 | 瑞禧生物 | 2023-03-17 |
5 | N3-PS-N3,Azido-PS-Azido/Azide,雙疊氮官能團修飾聚苯乙烯的制備方法 | 674 | 瑞禧生物 | 2023-03-17 |
6 | PS-N3,Azido-PS,疊氮Azide修飾聚苯乙烯/高分子聚合物的制備過程 | 847 | 瑞禧生物 | 2023-03-17 |
7 | Azido-PEG2-t-Butylester/1271728-79-0,疊氮N3/ZAD修飾叔丁酯化合物的制備方法 | 688 | 瑞禧生物 | 2023-03-14 |